The Benefits of Feeding Technology for Your Screening:

High product yield

Continuous nutrient release to ensure optimal product formation.

Various substrates and release rates

Kuhner Feeding Technology allows the release of various nutrients at different release rates without using foreign enzymes or pumps.

Higher reproducibility in screening

Adapting the preculture in fed-batch mode increases the reproducibility of the main culture.

Selection of the best strain

Quick and reliable finding of the optimal production strain.

Avoidance of negative process influences

Lower risk of an oxygen limitation and reduction of undesired by-products.

Fast and easily integrated in the laboratory

Sterilely packaged and easily to handle, the technology is usable with standard laboratory equipment.

Reduction of costs

Low investment costs and avoidance of unforeseen development costs.

Simple scale-up under process-related conditions

Time savings and cost reduction in bioprocess development through an easy transfer of results.

Comparable conditions between production and screening

Comparable cell metabolism in screening and production.

Better screening results

Cultivation conditions determine which cell strain makes the race

Kuhner Feeding Technology makes screening conditions more comparable to those on a production scale, avoiding overflow metabolism, pH inhibition and oxygen limitation. Thus, the optimal strain for a fed-batch bioprocess can be identified already early on. Comparable and reproducible cultivation conditions in the screening allow the identification of the optimal production strain at an early stage. As a result, costs and time-consuming process adaptions are reduced during later process development.